PRNewsWire
02 Jul 2026, 01:00 UTC · 3h ago
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Abbisko Therapeutics and AstraZeneca have entered a strategic collaboration to conduct a Phase I/II clinical trial combining the oral PD-L1 inhibitor lumipodlin (ABSK043) with Tagrisso (osimertinib) for NSCLC. — Validation from a global giant like AstraZeneca significantly derisks Abbisko's lead candidate and provides a clear path toward commercialization.
+0.60Lumipodlin is a potentially first-in-class oral small-molecule PD-L1 inhibitor, whereas current approved PD-1/PD-L1 drugs are monoclonal antibodies. — An oral alternative to injectable biologics represents a major shift in patient convenience and delivery, expanding the potential market for PD-L1 inhibition.
+0.40The National Medical Products Administration (NMPA) cleared the investigational new drug (IND) application for this combination study on May 20, 2026. — Regulatory clearance is a necessary milestone that allows the trial to proceed, reducing immediate administrative risk.
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The company entered a strategic collaboration with AstraZeneca to conduct clinical trials for its first-in-class oral PD-L1 inhibitor.
The company is expanding the clinical application of its drug Tagrisso through a strategic partnership to address unmet medical needs in NSCLC.
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