PRNewsWire
03 Jun 2026, 04:03 UTC · 2h ago
Johnson & Johnson presents new data further reinforcing the role of nipocalimab in lowering the autoantibodies driving Sjögren's disease
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PRNewsWire
03 Jun 2026, 04:03 UTC · 2h ago
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Johnson & Johnson reported that nipocalimab achieved a 62.5% response rate in the autoantibody-high subgroup compared to 51.9% in the overall Phase 2 DAHLIAS population. — Stronger-than-average efficacy in a high-burden subgroup increases the probability of success for the ongoing Phase 3 trial.
+0.60Nipocalimab is currently being evaluated in the Phase 3 DAFFODIL study for the management of systemic Sjögren's disease. — Progression to Phase 3 indicates a high-value pipeline asset moving closer to potential commercialization and FDA approval.
+0.30New biomarker analyses suggest nipocalimab's mechanism of action effectively reduces pathogenic IgG autoantibodies while preserving broader immune function. — Validation of the drug's biological mechanism reduces clinical risk and supports the targeted nature of the therapy.
+0.20Ticker attribution
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The company announced positive Phase 2 biomarker data for nipocalimab in treating Sjögren's disease, supporting its continued development.
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